{"id":60369,"date":"2024-04-15T19:01:54","date_gmt":"2024-04-15T23:01:54","guid":{"rendered":"https:\/\/textiles.ncsu.edu\/?p=60369"},"modified":"2024-04-18T23:13:51","modified_gmt":"2024-04-19T03:13:51","slug":"faculty-member-uses-dyes-to-research-degenerative-disease","status":"publish","type":"post","link":"https:\/\/textiles.ncsu.edu\/news\/2024\/04\/faculty-member-uses-dyes-to-research-degenerative-disease\/","title":{"rendered":"Faculty Member Uses Dyes to Research Degenerative Diseases"},"content":{"rendered":"\n\n\n\n\n

When the average person thinks of dyes, they likely think of hair and textiles. Associate Professor Nelson Vinueza<\/a> knows they have the power to do so much more. <\/p>\n\n\n\n

\u201cI build bridges between different research fields to see how we can make dyes more useful,\u201d Vinueza says of his research group at the Wilson College of Textiles. <\/p>\n\n\n\n

It is this ability to push impactful and interdisciplinary research forward that played a huge role in NC State University\u2019s decision to name him a University Faculty Scholar<\/a> in 2022.<\/p>\n\n\n\n

From forensics to disease<\/h3>\n\n\n\n

Vinueza, who holds a joint faculty appointment in the Wilson College and the College of Science\u2019s Department of Chemistry, was first recruited to NC State University for his expertise in analytical, organic and forensic chemistry as part of the Chancellor\u2019s Excellence Faculty Program<\/a>. By using analytical chemistry, forensic scientists can determine the substances present in clothes, upholstery and other textiles in order to provide more evidence to investigators. Vinueza Labs<\/a> focuses specifically on developing ways to discern information from trace amounts of dye present on tiny fiber samples \u2013 shorter than a millimeter, to be exact.\u00a0<\/p>\n\n\n\n

Vinueza says what drew him to NC State over other institutions was the wide range of interdisciplinary research he could engage in because of the college\u2019s focus on all aspects of textiles. He quickly focused on figuring out how he could apply his specialization in analytical and organic chemistry to a diverse range of research interests for Vinueza Labs.<\/p>\n\n\n\n

\"Nelson<\/figure>\n\n\n\n

\u201cWhen I identify a research gap that I can close, that’s when research becomes really exciting to me, because that\u2019s when I know I have something to give to society,\u201d he says.<\/p>\n\n\n\n

He\u2019s identified one such research gap within sustainability: researching how the use of dyes impacts our planet. <\/p>\n\n\n\n

 \u201cI want to know what happens to a dye that is in a fabric and how it bio-degrades into the soil to understand landfill degradation with textiles and their potential role as emerging contaminants,\u201d he explains. <\/p>\n\n\n\n

His largest ongoing research project, however, could make a significant impact on health and medicine. Through a project funded by the National Institutes of Health (NIH), Vinueza and his team of researchers are working with scientists from the University of California at San Francisco to identify potential treatments for degenerative diseases such as cataracts. <\/p>\n\n\n\n

\u201cIn this case, this research uses Differential Scanning Fluorimetry (DSF), which is a particularly versatile technique which reports protein thermal unfolding via fluorogenic dye. The dye acts as a sort of probe to help us see if a protein is unfolding,\u201d he says.<\/p>\n\n\n\n

A one-of-a-kind research resource<\/strong><\/h3>\n\n\n\n

The NIH project is just one of a number that has been made possible by the Max A. Weaver Dye Library, where Vinueza serves as director. <\/p>\n\n\n\n

The library houses a collection of dye fabric samples, testing data and more than 90,000 dyes donated by industry giant Eastman Chemical in 2014. The dyes, which were created over a period of 40 years, were custom manufactured, meaning that they provide one-of-a-kind research data. <\/p>\n\n\n\n

Naturally, this has made the library a destination for researchers from prestigious universities across the world, including Johns Hopkins to the University of Leeds. And much of Vinueza\u2019s work aims to make this library an even more useful tool for these visitors. Research assistants in Vinueza Labs are not only digitizing the library but also helping to identify connections for those using it. This unique dye database, which now includes nearly 8,000 dyes, is being used for more than a dozen collaborations outside NC State.<\/p>\n\n\n\n

<\/div><\/div>\"VialsPlay Video<\/title><\/path><\/svg><\/span><\/a><\/div><\/figure><\/div>\n\n\n\n

Fostering independent researchers\u00a0<\/strong><\/h3>\n\n\n\n

Despite the amount and caliber of research he publishes now, Vinueza began his doctoral program at Purdue University with no aspirations of becoming a professor.<\/p>\n\n\n\n

\u201cMy goal was to finish my Ph.D., go back to Ecuador, and make my career in industry because that\u2019s what we\u2019re all about. In Ecuador, we want to have something more. We want to have our own company or business,\u201d Vinueza says. \u201cIn my case, my aim was to open a cosmetic company.\u201d<\/p>\n\n\n\n

Purdue and his advisor, however, quickly opened his eyes to the possibilities of research and made him realize his love of mentoring and teaching. <\/p>\n\n\n\n

It\u2019s no surprise, then, that Vinueza takes a purposeful and thoughtful approach to his research assistants\u2019 experience in his research group. <\/p>\n\n\n\n

\u201cThe way I mentor my students on the graduate level is that they have to become independent scientists who solve problems,\u201d he says. <\/p>\n\n\n\n

\"A<\/figure>\n\n\n\n

In order to do that, he assigns each graduate student responsibility for a different mass spectrometer within his lab each year. Students gain hands-on experience with these sophisticated instruments, learning how they work and how to troubleshoot or repair them. <\/p>\n\n\n\n

\u201cYou can learn about instrumentation by learning how to operate, fix and adapt new hardware,\u201d he explains. \u201cYou also become familiar with having a leadership role and solving problems because you become the go-to person for other people in the lab on that piece of equipment.\u201d<\/p>\n\n\n\n

Vinueza\u2019s graduate students also play a crucial role in providing initial training for undergraduate research assistants. He pairs each undergraduate student with a graduate student whose project matches their interests and experience.\u00a0<\/p>\n\n\n\n

\"Nelson<\/figure>\n\n\n\n

\u201cMy research team takes care of each other and everybody has each other\u2019s back,\u201d he says. \u201cIf something goes wrong, everybody helps.\u201d<\/p>\n\n\n\n

Despite all his success in research, it\u2019s the seeing growth in his students that Vinueza says motivates him to do his best each day.<\/p>\n\n\n\n

\u201cI see the value of every person here, and that\u2019s what I\u2019d like to promote,\u201d he says. \u201cI think the most rewarding outcome of my work is to see later how successful your students become.\u201d <\/p>\n","protected":false,"raw":"\n\n\n\n\n

When the average person thinks of dyes, they likely think of hair and textiles. Associate Professor Nelson Vinueza<\/a> knows they have the power to do so much more. <\/p>\n\n\n\n

\u201cI build bridges between different research fields to see how we can make dyes more useful,\u201d Vinueza says of his research group at the Wilson College of Textiles. <\/p>\n\n\n\n

It is this ability to push impactful and interdisciplinary research forward that played a huge role in NC State University\u2019s decision to name him a University Faculty Scholar<\/a> in 2022.<\/p>\n\n\n\n

From forensics to disease<\/h3>\n\n\n\n

Vinueza, who holds a joint faculty appointment in the Wilson College and the College of Science\u2019s Department of Chemistry, was first recruited to NC State University for his expertise in analytical, organic and forensic chemistry as part of the Chancellor\u2019s Excellence Faculty Program<\/a>. By using analytical chemistry, forensic scientists can determine the substances present in clothes, upholstery and other textiles in order to provide more evidence to investigators. Vinueza Labs<\/a> focuses specifically on developing ways to discern information from trace amounts of dye present on tiny fiber samples \u2013 shorter than a millimeter, to be exact.\u00a0<\/p>\n\n\n\n

Vinueza says what drew him to NC State over other institutions was the wide range of interdisciplinary research he could engage in because of the college\u2019s focus on all aspects of textiles. He quickly focused on figuring out how he could apply his specialization in analytical and organic chemistry to a diverse range of research interests for Vinueza Labs.<\/p>\n\n\n\n

\"Nelson<\/figure>\n\n\n\n

\u201cWhen I identify a research gap that I can close, that's when research becomes really exciting to me, because that\u2019s when I know I have something to give to society,\u201d he says.<\/p>\n\n\n\n

He\u2019s identified one such research gap within sustainability: researching how the use of dyes impacts our planet. <\/p>\n\n\n\n

 \u201cI want to know what happens to a dye that is in a fabric and how it bio-degrades into the soil to understand landfill degradation with textiles and their potential role as emerging contaminants,\u201d he explains. <\/p>\n\n\n\n

His largest ongoing research project, however, could make a significant impact on health and medicine. Through a project funded by the National Institutes of Health (NIH), Vinueza and his team of researchers are working with scientists from the University of California at San Francisco to identify potential treatments for degenerative diseases such as cataracts. <\/p>\n\n\n\n

\u201cIn this case, this research uses Differential Scanning Fluorimetry (DSF), which is a particularly versatile technique which reports protein thermal unfolding via fluorogenic dye. The dye acts as a sort of probe to help us see if a protein is unfolding,\u201d he says.<\/p>\n\n\n\n

A one-of-a-kind research resource<\/strong><\/h3>\n\n\n\n

The NIH project is just one of a number that has been made possible by the Max A. Weaver Dye Library, where Vinueza serves as director. <\/p>\n\n\n\n

The library houses a collection of dye fabric samples, testing data and more than 90,000 dyes donated by industry giant Eastman Chemical in 2014. The dyes, which were created over a period of 40 years, were custom manufactured, meaning that they provide one-of-a-kind research data. <\/p>\n\n\n\n

Naturally, this has made the library a destination for researchers from prestigious universities across the world, including Johns Hopkins to the University of Leeds. And much of Vinueza\u2019s work aims to make this library an even more useful tool for these visitors. Research assistants in Vinueza Labs are not only digitizing the library but also helping to identify connections for those using it. This unique dye database, which now includes nearly 8,000 dyes, is being used for more than a dozen collaborations outside NC State.<\/p>\n\n\n\n

<\/div><\/div>\"VialsPlay Video<\/title><\/path><\/svg><\/span><\/a><\/div><\/figure><\/div>\n\n\n\n

Fostering independent researchers\u00a0<\/strong><\/h3>\n\n\n\n

Despite the amount and caliber of research he publishes now, Vinueza began his doctoral program at Purdue University with no aspirations of becoming a professor.<\/p>\n\n\n\n

\u201cMy goal was to finish my Ph.D., go back to Ecuador, and make my career in industry because that\u2019s what we\u2019re all about. In Ecuador, we want to have something more. We want to have our own company or business,\u201d Vinueza says. \u201cIn my case, my aim was to open a cosmetic company.\u201d<\/p>\n\n\n\n

Purdue and his advisor, however, quickly opened his eyes to the possibilities of research and made him realize his love of mentoring and teaching. <\/p>\n\n\n\n

It\u2019s no surprise, then, that Vinueza takes a purposeful and thoughtful approach to his research assistants\u2019 experience in his research group. <\/p>\n\n\n\n

\u201cThe way I mentor my students on the graduate level is that they have to become independent scientists who solve problems,\u201d he says. <\/p>\n\n\n\n

\"A<\/figure>\n\n\n\n

In order to do that, he assigns each graduate student responsibility for a different mass spectrometer within his lab each year. Students gain hands-on experience with these sophisticated instruments, learning how they work and how to troubleshoot or repair them. <\/p>\n\n\n\n

\u201cYou can learn about instrumentation by learning how to operate, fix and adapt new hardware,\u201d he explains. \u201cYou also become familiar with having a leadership role and solving problems because you become the go-to person for other people in the lab on that piece of equipment.\u201d<\/p>\n\n\n\n

Vinueza\u2019s graduate students also play a crucial role in providing initial training for undergraduate research assistants. He pairs each undergraduate student with a graduate student whose project matches their interests and experience.\u00a0<\/p>\n\n\n\n

\"Nelson<\/figure>\n\n\n\n

\u201cMy research team takes care of each other and everybody has each other\u2019s back,\u201d he says. \u201cIf something goes wrong, everybody helps.\u201d<\/p>\n\n\n\n

Despite all his success in research, it\u2019s the seeing growth in his students that Vinueza says motivates him to do his best each day.<\/p>\n\n\n\n

\u201cI see the value of every person here, and that\u2019s what I\u2019d like to promote,\u201d he says. \u201cI think the most rewarding outcome of my work is to see later how successful your students become.\u201d <\/p>\n"},"excerpt":{"rendered":"

Nelson Vinueza, associate professor at NC State University, analyzes dyes to uncover valuable findings in health, forensics and sustainability. <\/p>\n","protected":false},"author":12,"featured_media":60370,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"source":"","ncst_custom_author":"Sarah Stone","ncst_show_custom_author":true,"ncst_dynamicHeaderBlockName":"ncst\/default-post-header","ncst_dynamicHeaderData":"{\"displayCategoryID\":512,\"showAuthor\":true,\"showDate\":true,\"showFeaturedVideo\":false}","ncst_content_audit_freq":"","ncst_content_audit_date":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[742,490,512,479],"tags":[1143,2327,2328,504,505,544,1382],"displayCategory":{"term_id":512,"name":"Research and Innovation","slug":"research-and-innovation","term_group":0,"term_taxonomy_id":512,"taxonomy":"category","description":"","parent":0,"count":224,"filter":"raw"},"acf":[],"yoast_head":"Faculty Member Uses Dyes to Research Degenerative Diseases - Wilson College of Textiles<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/textiles.ncsu.edu\/news\/2024\/04\/faculty-member-uses-dyes-to-research-degenerative-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Faculty Member Uses Dyes to Research Degenerative Diseases - Wilson College of Textiles\" \/>\n<meta property=\"og:description\" content=\"Nelson Vinueza, associate professor at NC State University, analyzes dyes to uncover valuable findings in health, forensics and sustainability.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/textiles.ncsu.edu\/news\/2024\/04\/faculty-member-uses-dyes-to-research-degenerative-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"Wilson College of Textiles\" \/>\n<meta property=\"article:published_time\" content=\"2024-04-15T23:01:54+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-04-19T03:13:51+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/tex-cloud-cdn.nyc3.digitaloceanspaces.com\/textiles-ncsu\/20240415182447\/IMG_8862-Enhanced-NR-2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1500\" \/>\n\t<meta property=\"og:image:height\" content=\"844\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Wilson College Communications\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Wilson College Communications\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/textiles.ncsu.edu\/news\/2024\/04\/faculty-member-uses-dyes-to-research-degenerative-disease\/\",\"url\":\"https:\/\/textiles.ncsu.edu\/news\/2024\/04\/faculty-member-uses-dyes-to-research-degenerative-disease\/\",\"name\":\"Faculty Member Uses Dyes to Research Degenerative Diseases - 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