Yang Zhang

Bio

Dr. Yang Zhang develops fluorescent & stimuli-responsive materials and single-molecule methods to color-map and engineer the nanoscopic biological and man-made world, especially nanofiber networks in the subcellular level including DNA, cytoskeleton and cell membranes. We are also interested in imaging biocompatible textile-nanofiber and understanding their nanoscopic structure-function relationships in biomedical and energy-related applications.

Detailed research directions please visit our group page https://sites.google.com/view/mapperncsu

Publications

• Framework for Accurate Single-Molecule Spectroscopic Imaging Analyses Using Monte Carlo Simulation and Deep Learning , ANALYTICAL CHEMISTRY (2025)
• Mineral Deposition from Liquid Precursors Triggered by Complementary Polyelectrolytes , (2025)
• Photoactivation of BODIPY Fluorescence with Green Light , JOURNAL OF ORGANIC CHEMISTRY (2025)
• Photoswitchable Fluorescent Hydrazone for Super-Resolution Cell Membrane Imaging , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2025)
• Solvatochromic BODIPYs with Polarity-Independent Absorption for Functional Super-resolution Imaging of Live Cell Membranes , Chemical & Biomedical Imaging (2025)
• Multiscale imaging of corneal endothelium damage and Rho-kinase inhibitor application in mouse models of acute ocular hypertension , BIOMEDICAL OPTICS EXPRESS (2024)
• Quantifying nanoscopic alterations associated with mitochondrial dysfunction using three-dimensional single-molecule localization microscopy , BIOMEDICAL OPTICS EXPRESS (2024)
• Integrating Machine Learning and Color Chemistry: Developing a High-School Curriculum toward Real-World Problem-Solving , JOURNAL OF CHEMICAL EDUCATION (2023)
• Investigating Uncertainties in Single-Molecule Localization Microscopy Using Experimentally Informed Monte Carlo Simulation , NANO LETTERS (2023)
• Nucleoporin downregulation modulates progenitor differentiation independent of nuclear pore numbers , COMMUNICATIONS BIOLOGY (2023)

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