Nelson Vinueza Benitez
Bio
Research in the Vinueza group centers around three aspects of mass spectrometry (MS): fundamentals, instrumentation and applications. Fundamental studies aimed to enhance the analytical capabilities of mass spectrometry focus on the characterization of dyes from the recent donated Max Weaver dye library, with around 100,000 dyes. Instrumentation development includes a wide range of projects in tandem mass spectrometry (MS/MS), chromatography and microfluidics. We are currently utilizing microfluidics to extract dyes from fibers in combination with a quadrupole-time-of-flight for a faster characterization. Applications of MS techniques developed in our group include studies in biofuels and forensic analysis. Current projects include characterization of bio-oil from lignocellulose biomass, sequencing of oligosaccharides and fast analysis of chemicals of forensic interest, such as dyes, inks, fibers, polymers and drugs. These applications involve direct collaboration with colleagues in other departments on campus and around the world. Mass spectrometry, chromatography, FT-Raman, FT-IR, organic synthesis and gas-phase ion chemistry are central tools for the lab.Research
Teaching
Education
Post-doctoral fellow C3Bio, DOE EFRC (Energy Frontiers Research Center) Research Focus: Develop mass spectrometry methods for the analysis of lignin and cellulose degradation products as well as bio-oil Purdue University 2012
Ph.D. Physical Organic Chemistry Purdue University 2010
Dissertation Reactivity Studies of Charged σ,σ,σ-Triradicals Using the Distonic Ion Approach and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
B.S. Chemical Engineering Universidad San Francisco de Quito, Quito-Ecuado 2003
B.S. Industrial Chemistry Universidad San Francisco de Quito, Quito-Ecuado 2001
Area(s) of Expertise
Analytical Chemistry
Color Science
Dyeing and Finishing
Forensics
Sustainability
Textile Chemistry
Publications
- A Selective, Class-Specific Aptamer for Fentanyl Analog Screening , Analytical Chemistry (2026)
- Author Correction: High-throughput discovery of fluoroprobes that recognize amyloid fibril polymorphs , Nature Chemistry (2026)
- Direct Analysis of Basic Dyes and Photodegradation Products in Blue Ballpoint Inks via Desorption Electrospray Ionization Mass Spectrometry , Journal of the American Society for Mass Spectrometry (2026)
- Aurora 2.0: A fluorogenic dye library for expanding the capability of protein-adaptive differential scanning fluorimetry (paDSF) , SLAS DISCOVERY (2025)
- BPS2025 - Expansion of a chemically diverse fluoroprobe library to further utilize protein-adaptive differential scanning fluorimetry (paDSF) , Biophysical Journal (2025)
- High-Contrast Aptamer-Based Merocyanine Displacement Assays for Sensitive Small Molecule Detection , ACS Sensors (2025)
- High-throughput discovery of fluoroprobes that recognize amyloid fibril polymorphs , Nature Chemistry (2025)
- Impaired cell viability and mitochondrial respiration by disperse textile dyes , Frontiers in Allergy (2025)
- Solvatochromic BODIPYs with Polarity-Independent Absorption for Functional Super-resolution Imaging of Live Cell Membranes , Chemical & Biomedical Imaging (2025)
- The importance of the YG1041 Salmonella strain in the mutagenicity characterization of azo dyes , Food and Chemical Toxicology (2025)