Bio

Dr. Yang Zhang develops fluorescent & stimuli-responsive materials and single-molecule methods to color-map and engineer the nanoscopic biological and man-made world, especially nanofiber networks in the subcellular level including DNA, cytoskeleton and cell membranes. We are also interested in imaging biocompatible textile-nanofiber and understanding their nanoscopic structure-function relationships in biomedical and energy-related applications.

Detailed research directions please visit our group page https://sites.google.com/view/mapperncsu

Publications

• Accurate and Robust Measurement of Single-Molecule Fluorescence Spectral Heterogeneity , ACS Measurement Science Au (2026)
• BPS2026 - Integrating spectroscopic single-molecule localization microscopy with DNA-PAINT for simultaneous multiplexing super-resolution microscopy , Biophysical Journal (2026)
• Charge Imbalance Drives Salt-Optimized Nucleosome Phase Separation under Physiological Conditions , bioRxiv (Cold Spring Harbor Laboratory) (2026)
• Correction to “Photoswitchable Fluorescent Hydrazone for Super-Resolution Cell Membranes Imaging” , Journal of the American Chemical Society (2026)
• Mineral Deposition From Liquid Precursors Triggered by Complementary Polyelectrolytes , Advanced Functional Materials (2026)
• Photoactivatable BODIPY Dyes Conjugated to Self-Labeling Protein Tags , ACS Applied Bio Materials (2026)
• SIMBA: an agentic AI platform for single-molecule multi-dimensional imaging , bioRxiv (Cold Spring Harbor Laboratory) (2026)
• Spectroscopic DNA-PAINT for Simultaneous Multiplexed Super-Resolution Microscopy , Nano Letters (2026)
• Spectroscopic DNA-PAINT for simultaneous multiplexed super-resolution microscopy , bioRxiv (Cold Spring Harbor Laboratory) (2026)
• Framework for Accurate Single-Molecule Spectroscopic Imaging Analyses Using Monte Carlo Simulation and Deep Learning , Analytical Chemistry (2025)